Hi Peggy
Thanks for the advine! So I will feel free to enjoy my cup of coffe :-) and
no coke or sodas any more, I will try to get away frim sugars and that
stuff I promisse it every day :-(
By
Have a nice day
Best regards
Erika Klinge.
phone: (511) 617 2500 (137)
cell: (511) 9404*3124
www.Thimblesourcing.com
_____
I meant osteoclasts not osteoblasts.
Apparently in a effort to do their job more osteoblasts become active
due the inhibition of their activity by the PPI class of medications.
The effect on balance apparently weakens the bones.
1: JAMA. 2006 Dec 27;296(24):2947-53.
Long-term proton pump inhibitor therapy and risk of hip fracture.
Yang YX, Lewis JD, Epstein S, Metz DC.
Division of Gastroenterology, Center for Clinical Epidemiology and
Biostatistics, University of Pennsylvania School of Medicine,
Philadelphia 19104, USA.
yangy@...
CONTEXT:
Proton pump inhibitors (PPIs) may interfere with calcium absorption
through induction of hypochlorhydria but they also may reduce bone
resorption through inhibition of osteoclastic vacuolar proton pumps.
OBJECTIVE:
To determine the association between PPI therapy and risk of hip
fracture.
DESIGN, SETTING, AND PATIENTS:
A nested case-control study was conducted using the
General Practice Research Database (1987-2003), which contains
information on patients in the United Kingdom. The study cohort
consisted of users of PPI therapy and nonusers of acid suppression
drugs who were older than 50 years.
Cases included all patients with an incident hip fracture. Controls
were selected using incidence density sampling, matched for sex,
index date, year of birth, and both calendar period and duration of
up-to-standard follow-up before the index date. For comparison
purposes, a similar nested case-control analysis for histamine 2
receptor antagonists was performed.
MAIN OUTCOME MEASURE:
The risk of hip fractures associated with PPI use.
RESULTS: There were 13,556 hipfracture cases and 135,386 controls.
The adjusted odds ratio (AOR) for hipfracture associated with more
than 1 year of PPI therapy was 1.44 (95%confidence interval [CI],
1.30-1.59). The risk of hip fracture was significantlyincreased among
patients prescribed long-term high-dose PPIs (AOR, 2.65; 95% CI,1.80-
3.90; P<.001). The strength of the association increased with
increasing duration of PPI therapy (AOR for 1 year, 1.22 [95% CI,
1.15-1.30]; 2 years, 1.41 [95% CI, 1.28-1.56]; 3 years, 1.54 [95% CI,
1.37-1.73]; and 4 years, 1.59 [95% CI, 1.39-1.80]; P<.001 for all
comparisons).
CONCLUSION: Long-term PPI therapy, particularly at high doses, is
associated with an increased risk of hip fracture.
PMID: 17190895 [PubMed - indexed for MEDLINE
Hi all!
Does any one know if drinking a cup of coffe and a diet coke every day will
reduce calcium absorption?
Pls advice! Also which other food reduce calcium absorption or is bad to
consolidate bones,,.
I was told that sardines are good and high in clacium
Also I bought ultramegas bone density in GNC which is very complete in
calcium and minerals, (all the ones Johan advice and some more) may be this
will help Lo
Have a nice day :-)
Best regards
Erika Klinge.
THIMBLE - ISLANDS
Phone:(511) 617-2500 ext.137
Cellphone: (511) 9404*3124
<BLOCKED::http://www.thimble-islands.com/
_____
Hi Anne,
I am glad to hear you pulling out of the anorexia. It is a tough thing. I am
34 years old with osteopenia, a result of anorexia. I took Boniva and Fosomax at
different times. I would really suggest discussing the effects on pregnancy with
your doctor. I have had 2 children but was not on medication while pregnant. If
you get pregnant, calcium will be very important. If you want to contact me for
support for the anorexia, I can be there. Good luck.
Tara
anne catherine <lucillec2002@...
Hi all-
My name is Anne and I'm a 31 year old in NYC with osteoperosis (not penia...
perosis). I've been taking Boniva for a few months. I'm pretty anxious about it,
as I worry about how new it is, and the fact that it's not yet known what affect
it may have on women who become pregnant. I'm not pregnant, but would like to
become so in the next few years. Does anyone know anything about taking cal.
medication during childbearing years? Any info. would be appreciated. I'm rather
down about this, and angry at myself since the osteoperosis was the result of
anorexia, which I'm finally pulling out of (but, of course, living with the
health after-effects).
Happy new year everyone,
Anne
Dear Farah,
The product I use is called OsteoVite and I have a suspicion that it is
a product made locally in South Africa. However, I can get it at most
pharmacies and health shops here in Johannesburg.
Regards,
Johan
Hi all-
My name is Anne and I'm a 31 year old in NYC with osteoperosis (not penia...
perosis). I've been taking Boniva for a few months. I'm pretty anxious about it,
as I worry about how new it is, and the fact that it's not yet known what affect
it may have on women who become pregnant. I'm not pregnant, but would like to
become so in the next few years. Does anyone know anything about taking cal.
medication during childbearing years? Any info. would be appreciated. I'm rather
down about this, and angry at myself since the osteoperosis was the result of
anorexia, which I'm finally pulling out of (but, of course, living with the
health after-effects).
Happy new year everyone,
Anne
Dear Johan
Please tell what is your calcium supplement name in the store.
Farah
Hi, Erika,
The product I use is called OsteoVite and I have a suspicion that it is
a product made locally in South Africa. However, I can get it at most
pharmacies and health shops here in Johannesburg.
Regards,
Johan
Hi JOhan,
Sounds very good that complement of calcium + minerals + stuff
Can you sent me please the name of that complex and where to find this
please
Thanks a lot :-)
Happy new year!!!
Best regards
Erika Klinge.
THIMBLE - ISLANDS
Phone:(511) 617-2500 ext.137
Cellphone: (511) 9404*3124
<BLOCKED::http://www.thimble-islands.com/
_____